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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM48
All Species:
7.58
Human Site:
S417
Identified Species:
16.67
UniProt:
Q9BTX1
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BTX1
NP_060557.2
674
76305
S417
T
A
F
Q
T
P
K
S
S
Q
M
P
R
P
S
Chimpanzee
Pan troglodytes
XP_513417
776
87618
S519
T
T
F
Q
T
P
K
S
S
Q
M
P
R
P
S
Rhesus Macaque
Macaca mulatta
XP_001091911
530
59703
L281
W
L
C
G
V
F
L
L
M
T
W
Y
I
S
W
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q8VCB1
673
75391
P418
T
A
F
Q
T
P
K
P
S
Q
T
P
S
V
P
Rat
Rattus norvegicus
Q6AXN4
673
75694
P418
T
A
F
Q
T
P
K
P
S
Q
M
P
S
V
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518195
431
47121
S180
V
V
P
S
P
P
C
S
R
L
T
L
L
G
K
Chicken
Gallus gallus
XP_001235442
684
77153
S428
I
P
F
Q
L
Q
R
S
N
V
I
P
R
A
A
Frog
Xenopus laevis
Q6AX31
660
74320
N411
D
S
A
E
Q
T
Q
N
L
S
T
I
P
R
I
Zebra Danio
Brachydanio rerio
Q7SZC5
671
74423
P414
D
V
P
E
T
P
R
P
T
V
P
L
R
T
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VCG4
578
65368
Q329
A
L
R
K
N
S
P
Q
R
A
E
I
F
Q
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784037
756
85199
R506
P
F
V
F
L
Q
P
R
I
A
V
I
R
Q
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86
76.4
N.A.
N.A.
87
86.9
N.A.
20.4
67.8
56.8
53.5
N.A.
22.7
N.A.
N.A.
28.1
Protein Similarity:
100
86.2
77.3
N.A.
N.A.
92.1
92.5
N.A.
33.5
79.3
72.4
72.2
N.A.
43.4
N.A.
N.A.
45.3
P-Site Identity:
100
93.3
0
N.A.
N.A.
66.6
73.3
N.A.
13.3
33.3
0
20
N.A.
0
N.A.
N.A.
6.6
P-Site Similarity:
100
93.3
0
N.A.
N.A.
66.6
73.3
N.A.
13.3
60
26.6
40
N.A.
6.6
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
28
10
0
0
0
0
0
0
19
0
0
0
10
10
% A
% Cys:
0
0
10
0
0
0
10
0
0
0
0
0
0
0
0
% C
% Asp:
19
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
19
0
0
0
0
0
0
10
0
0
0
0
% E
% Phe:
0
10
46
10
0
10
0
0
0
0
0
0
10
0
0
% F
% Gly:
0
0
0
10
0
0
0
0
0
0
0
0
0
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
0
0
0
0
0
10
0
10
28
10
0
10
% I
% Lys:
0
0
0
10
0
0
37
0
0
0
0
0
0
0
10
% K
% Leu:
0
19
0
0
19
0
10
10
10
10
0
19
10
0
19
% L
% Met:
0
0
0
0
0
0
0
0
10
0
28
0
0
0
0
% M
% Asn:
0
0
0
0
10
0
0
10
10
0
0
0
0
0
0
% N
% Pro:
10
10
19
0
10
55
19
28
0
0
10
46
10
19
28
% P
% Gln:
0
0
0
46
10
19
10
10
0
37
0
0
0
19
0
% Q
% Arg:
0
0
10
0
0
0
19
10
19
0
0
0
46
10
0
% R
% Ser:
0
10
0
10
0
10
0
37
37
10
0
0
19
10
19
% S
% Thr:
37
10
0
0
46
10
0
0
10
10
28
0
0
10
0
% T
% Val:
10
19
10
0
10
0
0
0
0
19
10
0
0
19
0
% V
% Trp:
10
0
0
0
0
0
0
0
0
0
10
0
0
0
10
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _